MSU Receives Funding to Expand Sequencing Capacity

Michigan State University researchers on the front lines in the battle for the health and safety of residents recently received some reinforcements.

Michigan State University researchers on the front lines in the battle for the health and safety of residents recently received some reinforcements.

MSU was named Jan. 5 among four Michigan universities to receive $18.5 million in federal funds over the next two years to collect and analyze genomic data to address emerging infectious disease threats and enhance the state’s ability to respond to those threats.

Along with Michigan Tech University, the University of Michigan and Wayne State University, MSU will use the funding to increase sequencing capacity in the state starting with to COVID-19 and then other infectious disease threats with the potential for broad community spread. Funding for the Michigan Sequencing Academic Partnership for Public Health Innovation and Response, known as MI-SAPPHIRE, is through a Centers for Disease Controls of Prevention epidemiology and laboratory capacity grant. The funding is being disbursed through the Michigan Department of Health and Human Services.

MI-SAPPHIRE activities will include sequence generation and analysis, such as sample collection and sequencing; data processing, storage and sharing; and data interpretation and analytics.

“The COVID-19 pandemic has highlighted the importance and need for genomic sequencing, surveillance and epidemiology capacity both globally and right here in Michigan,” said Elizabeth Hertel, MDHHS director. “The MDHHS Bureau of Laboratories has rapidly expanded its efforts to identify COVID-19 variants since the start of the pandemic to support public health actions. MI-SAPPHIRE will allow our state to expand sequencing and analysis capacity and the number of pathogens that undergo routine sequencing and ensure we are sampling diverse geographic areas across the state.”

MDHHS has been at the forefront in national sequencing and genomic epidemiology as the national center for tuberculosis sequencing, PulseNet foodborne pathogen regional center and COVID-19. The state generates over 25,000 genomes per year for bacterial and viral organisms. Partnerships with the four universities will allow for the scalability of capacity and response for COVID-19 and other pathogens.

The Bureau of Laboratories has sequenced 23,000 COVID-19 samples since March 2020. The University of Michigan lab has also conducted sequencing throughout the pandemic to provide information about COVID-19 variants circulating in the state.

Data generated or activities funded must support public health action, surveillance activities, infrastructure development or pandemic response efforts. Data or projects generated solely for research purposes and not directly actionable by state epidemiologists are not allowable with federal grant funds.

For more information on genetic sequencing, visit What is Genomic Surveillance? | CDC.

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